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The central innovation of POPE 13 C-MRS is the detection of heteronuclear 1 H- 13 C satellite resonances using targeted proton editing, enabling the simultaneous measurement of 13 C-labelling of metabolites such as glutamate, GABA and lactate while avoiding broadband 13 C excitation or decoupling

As SNpc DA neurons are scarcely or thinly myelinated, very few transplantation studies dealing with this neuronal population have assessed whether the grafts acquire myelination or affect the host OL population

doi: 10.3389/fimmu.2023.1148595 80 VairaLAGessaCDeianaGSalzanoGMaglittoFLechienJRvet al