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Funding This research was supported by NIA/NINDS RO1 AG061708 (P.H.O) and was made possible with the generous philanthropic support the Ozdinler Lab received from many different donors

Nature 447 (7143), 399406

Moreover, most of the natural products target all DNMT isoforms leading to a low specificity that might limit their potential use in clinical development

For years, compounding pharmacies (facilities that custom-mix medications for individual patients) served as the primary legal pipeline for peptides like BPC-157 and TB-500