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121 Monitoring is essential in patients receiving treatment for longer than 14 days, have pre-existing myelosuppression, take concurrent medications that cause myelosuppression, or have received prior antibiotic therapy from a chronic infection

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In addition, lactate plays a crucial role in increasing BDNF-induced benefits such as neurogenesis, neuronal survival, synaptic plasticity, and dendritic spine growth ( peak ) ( Figure 1 7 CREBs role on neuronal development- different types of HIT protocols CREB is crucial for neuronal development, and studies have shown that CREB deletion leads to neurodegeneration in the hippocampus and dentate gyrus ( 2+ and CaMK IV, may improve the functions of neurons by transcription of the BDNF gene mediated by CREB ( Figure 2 )