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Unless expressly stated to the contrary, substitution by a named substituent is permitted on any atom in a ring (e.g., aryl, a heteroaryl ring, or a saturated heterocyclic ring) provided such ring substitution is chemically allowed and results in a stable compound

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Oxidative stress in the pathogenesis of crohns disease and the interconnection with immunological response, microbiota, external environmental factors, and epigenetics

2.6 PICRUSt2 functional prediction analysis Phylogenetic studies of the cohort were performed by reconstructing the unobserved state 2 (PICRUST2) to predict the functional potential of the bacterial community