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The IGF-1 and HGH Connection About 70% of IGF-1 is produced by the liver in response to human growth hormone, which is produced in the pituitary gland

Ramasamy R, et al

Food Chemistry, 122: 987996

As discussed previously, unlike most of the surrounding tissue that is of mesenchymal origin, the NP arises from the notochord, which is a transient structure