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K.LayekB.et al

Direct immunofluorescence staining revealed a broad deposition of IgG along the basement membrane, broad perivascular deposition of IgG and IgA, weak perivascular deposition of IgM, and granular perivascular deposition of C3c

Together, these findings demonstrate that STK38 exerts its pro-death regulatory function through direct phosphorylation of RIPK1 at S309, which is required for the full activation of RIPK1 signalling during both necroptosis and apoptosis