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J Mol Med 77:495504 Hisano S, Daikoku S, Yanaihara N, Shibasaki T (1986) Intragranular colocalization of CRF and Met-Enk-8 in nerve terminals in the rat median eminence

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PNAs can be used as antisense or antigene agents for sequence-specific modulation of gene expression by, for example, inducing transcriptional or translational arrest or inhibiting replication

Laboratory protocols typically utilize dosing ranges that maintain safety margins while achieving research objectives, with careful attention to the compound's effects on hypothalamic-pituitary axis function