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doi: 10.1371/journal.pone.0182921 174 YuFWangCSuYChenTZhuWDongXet al

However, it appears that the profile of metabolic disturbances in such cases will be similar to that of COVID-19, as the process of pathogen persistence is very often associated with the blockade of autophagy by these pathogens (220225), which further leads to the induction of oxidative, nitrosative, Ca i 2+ and ER stress

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