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The brain is classified among the most generating organs for the reactive oxygen species (ROS), where 4% of the oxygen consumed by the mitochondria is converted into super oxide superoxide ion (O2), which possesses exceptionally high reactivity, particularly as a powerful oxidizing agent and an initiator of radical reactions

Glutathione S-transferase M1 (GSTM1) is another important metabolic enzyme gene that catalyzes the conjugation of glutathione with electrophilic compounds, converting activated carcinogens into inactive, water-soluble substances for excretion

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Ectopic expression of some of these cotton homologues alters trichome development in Arabidopsis (Wang et al., 2004