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268 Inflammatory cytokines (e.g., IL-6 and TNF-) upregulate the expression of CYP24A1 in colon cancer cells by activating the NF-B pathway, which in turn leads to abnormal activation of the Wnt/-catenin pathway and promotes disease progression

Overview of the types of white blood cells and where they are found in the body The infographic shows where white blood cells (WBCs) are made and found in the body, including the tonsils, lymph nodes, thymus, spleen, Peyers patches, lymph vessels, and bone marrow

Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer

It also plays a role in maintaining a stable heart rhythm and overall metabolic health