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Kinetics and mechanism of the decomposition of S-nitrosoglutathione by l-ascorbic acid and copper ions in aqueous solution to produce nitric oxide

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Additionally, designing cyclic peptides for active transport via peptide transporters (PepT1, PepT2) or exploiting transcytosis pathways can significantly improve oral bioavailability

This mechanism is particularly beneficial in treating conditions where enhanced blood flow is desired, such as in cardiovascular diseases, erectile dysfunction, and peripheral vascular disease