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These findings indicate that vascular contrast enhancement can be effectively achieved using KBiF 4 @HSA at low concentrations, whereas iohexol necessitates a significantly higher concentration to achieve visualization, which consequently elevates its toxicity within the body

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T2 hyperintensities in White matter, Basal ganglia, Thalamus, Brainstem Encephalopathy + Cardiomyopathy: Mitochondrial Complex IV Deficiency, Nuclear Type 22 (MC4DN22) (Complex IV) Cytochrome c Oxidase Assembly Factor 16 (COX16)