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Inhibitors Pieces of evidence for the transcriptional regulation of NRF2 highlighted that modifications of the NFE2L2 promoter region such as hypermethylation or single nucleotide polymorphisms, are responsible for a decreased NRF2 expression

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GSH can prevent and reduce cyto- and tissue toxicities produced by multiple pathways which, although different, share a capacity for amelioration by GSH by virtue of the carefully positioned thiol of GSH with a zwitterion from the gamma glutamyl residue

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