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Inherited loss-of-function mutations of CBS result in classical homocystinuria (HCU), the most common inborn error of sulfur metabolism 8

While its efficacy in treating acetaminophen overdose, cystic fibrosis, and chronic obstructive pulmonary disease is well-established, emerging evidence suggests that NAC may also benefit a broader spectrum of illnesses due to its safety, simplicity, and affordability

Variation of As concentration between soiltypes and ricegenotypes and the selection of cultivars for reducing As in the diet

The active site of GPX4, selenocysteine, alternates between reduced and oxidized states to sustain its catalytic activity