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Yokota T, Nara Y, Kashima A, Matsubara K, Misawa S, Kato R, et al

Does changing the amount of liquid change the dose

The recommended dose of ALIMTA for treatment of recurrent non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle until disease progression or unacceptable toxicity