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Some or all of these changes may contribute to alcohols toxic effects on the liver and to the development of liver fibrosis.4 Vitamin A Therapy Because alcohol consumption leads to reduced vitamin A levels in the liver, with potentially detrimental effects, it would appear plausible to treat alcoholics with extra vitamin A to compensate for alcohols effects

10.1007/s00109-016-1488-y 28 IlicS.BrcicI.MesterM.FilipovicM.SeverM.KlicekR.et al (2009)

Current clinical thresholds are summarised in Table 6

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