Elevated levels of HSP27 and HSP70 in breast cancer cell lines are associated with increased resistance to doxorubicin, independent of P-glycoprotein (P-gp), a key mediator of multidrug resistance (MDR)
Metabolites were analyzed using a targeted metabolite analysis method optimized to detect GR, SF and the six SF metabolites (sulforaphane N-acetyl-L-cysteine (SF-NAC), sulforaphane glutathione (SF-GSH), sulforaphane-L-cysteine (SF-Cys), sulforaphane-cysteinylglycine (SF-Cys-Gly), sulforaphane-glucuronide and sulforaphane-sulfate) by LCMS

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Regular or traditional oral glutathione supplements, however, face a significant hurdle: poor absorption