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Donors of other protein acylation The research on acyl-CoA of other short-chain acylations including lysine malonylation (Kmal), succinylation (Ksuc), crotonylation (Kcro), -hydroxybutyrylation (bhb) and lactylation (Klac) or long-chain acylation including myristoylation and palmitoylation is not so thorough and enough

Species differences in metabolism, receptor expression, and pharmacokinetics mean that effective doses in rats do not predict safe or effective doses in humans

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Based on findings reported to date, additional research is necessary to clarify the underlying mechanism