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2.3 CircRNAs that are potential biomarkers of ferroptosis Several studies have reported that a range of circRNAs exhibit abnormal expression levels in cells treated with ferroptosis inducers (Liu et al., 2020

Site S5 is composed of residues from the TrxR and Grx domains, lying over the FAD binding subdomain (Suppl

The katG gene, encoding HPI, has been found to be regulated by the OxyR regulon which responds to oxidative stress [9, 21, 22]

An interesting therapeutic strategy is to induce arginine transporters (e.g., Slc7a2) in antitumor T cells, before their adoptive transfer to patients, enhancing their ability to compete for arginine in the TME, without the deleterious effects of arginine depletion for antitumor immunity [8]