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doi: 10.1038/s41579-025-01174-x 141 SciavillaP.StratiF.Di PaolaM.ModestoM.VitaliF.CavalieriD.et al

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In vitro visualization of changes in lipid oxidation and labile iron in primary cells from PCBP1-deficient livers is a powerful approach to real-time monitoring of the function of the iron chaperone and intracellular redox status

Key findings include no serious adverse events related to AOD 9604

Furthermore, the application of Fer-1, an inhibitor of ferroptosis, was found to mitigate cellular damage associated with the knockout of the GPX4 gene (229)