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The mechanistic core of the finding was that Dihexa activated the PI3K/AKT signaling pathway in the brains of the APP/PS1 mice, and that the PI3K inhibitor wortmannin reversed Dihexas anti-inflammatory and anti-apoptotic effects [5]

Definition, epidemiology and classification of diabetes in children and adolescents

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Receptor activity profile: Acts as a nonselective agonist at amylin and calcitonin receptors involved in appetite regulation, gastric emptying, and metabolic control