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Hypoxia Chronic persistent or intermittent hypoxia (IH) triggers ECD leading to both inflammation and oxidative stress [131, 132]

Mechanism 2: Increased Follicle Enlargement Research published in the Journal of Investigative Dermatology found that GHK-Cu increased follicle size by approximately 46% in study models consistent with the known effect of vascular growth factors that GHK-Cu upregulates (VEGF in particular drives nutrient delivery to follicles)