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However, another study on 38 healthy people showed that the intake of up to three eggs per day did not increase TMAO levels, but had beneficial effects such as increasing HDLcholesterol and choline [44]

Moreover, consuming probiotics and prebiotics linked to certain genes that inhibit TMA-producing bacteria has also been shown in some studies to help control the generation of TMAO [112, 113]

Furthermore, L-carnitine as a potent antioxidant can decrease oxidation of purine and pyrimidine bases, breakage of DNA single and double strands, DNA fragmentation and protamine deficiency and maintain DNA integrity during cryopreservation by ROS reduction (78)