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Typical Dosing Range Recommended Starting Protocol Cycle length: 10 to 20 consecutive days Dose: 510 mg per day, subcutaneous injection Frequency of cycles: 12 cycles per year is the most commonly cited approach for longevity purposes

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HGF hepatocyte growth factor c-Met its type I tyrosine kinase-receptor HGF neuroprotective effect of the HGF on the nigrostriatal pathway, however, should be no surprise given its recognized role in stem cell regulation, the development of tubular structures (Santos et al., 1993) and its general proliferative, anti-apoptotic, motogenic, and morphogenic actions on many cell types including hepatocytes and cells of epithelial origin (Gherardi et al., 1993)

3 Data Sources : A PubMed search was completed in Clinical Queries using the key terms vitamin B 12 , cobalamin, deficiency, and treatment