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Increased iron in brain tissue causes reactive oxygen species (ROS) formation via Fenton reaction, inducing ferroptosis and finally leading to neurodegeneration (Kim et al., 2015

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The skin lightening market is worth an estimated R130 billion, and despite the many health risks associated with the practice, this number is expected to reach approximately R300 billion by the year 2020, according to a 2009 Global Industry Analysts report