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2012b;336(6078):2258

H.WeissmanJ

2012, Epub ahead of print Acknowledgements The authors would like to thank Jonathan Yingling for helpful scientific discussions, Jonathan Lee and Sarah Oliver for assay characterization and helpful discussions and Laura Benjamin and Bronek Pytowski for critical review of the manuscript

This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol