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Proc Natl Acad Sci U S A 95:84048409 Biterova EI, Barycki JJ (2009) Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase

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The effects of iron deficiency in tissues and reduced activity of iron-containing enzymes, such as growth retardation, abnormal behavior, and physical deficiency, can therefore be gradually corrected after active iron supplementation in iron-deficient animals, in addition to accelerating hemoglobin synthesis