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Other Treatments Arimoclomol is an investigational drug that improves the expression of heat shock proteins, thereby helping prevent the accumulation of misfolded proteins

So far, the FDA has primarily approved treatments for AD that focus on compensating for cholinergic neuron loss using drugs such as inhibitors for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), including medications like tacrine, donepezil, rivastigmine, and galantamine, as well as the glutamatergic drug memantine, which functions as an N-methyl-D-aspartate (NMDA) receptor antagonist (Albertini et al

[] Its expression is upregulated by HIF-1 and forkhead box protein O3 (FOXO3)

Simple: "It doesn't matter if you're doing an Arnold split or some crazy mix of parts