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Pappas et al., 2018)

A review of the medical examination data from 25 autistic children found that 53% of these patients had increased pyruvate levels, 76% had elevated blood lactate, in 20% of them the lactate/pyruvate ratio in fibroblasts was increased, and 42% were presented with atypical results of urine organic acid analysis [72]

A 2018 follow-up by the same authors in International Journal of Molecular Sciences extended the case with gene-expression data, showing GHK can up- or down-regulate thousands of genes implicated in skin regeneration and inflammation (Pickart et al., 2018)