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Nutrients 11 , 1742 (2019)

Heterogeneity and clonality of kidney-infiltrating T cells in murine lupus nephritis

HDAC inhibition increases acetylation of the NR3C1 gene (encoding the glucocorticoid receptor), enhancing glucocorticoid receptor sensitivity and restoring the negative feedback of the hypothalamic-pituitary-adrenal (HPA) axis