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The involved signaling pathways are quite diverse, promoting not only the production of inflammatory factors (IL-8, IL-6, and IL-1), but also the activation of granulocytemacrophage colony-stimulating factor, monocyte chemotaxis protein-1 (CCL2), macrophage movement inhibitory factor (MIF), TNF-, and tumor growth factor- (TGF-

The Microbial Organic Acids Test (MOAT) is ideal for a follow-up to the OAT and is often recommended by practitioners looking for a specific abnormality, to monitor certain microbial imbalances, or to assess treatment efficacy

Hanczko R, Fernandez DR, Doherty E, Qian Y, Vas G, Niland B, et al

Furthermore, with large-scale drug use it is inevitable that PZQ-resistant parasites will evolve, and PZQ resistance has been induced in laboratory infections 12