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Front Endocrinol (Lausanne) (2022) 13:813057

Ma C, Zhang X, Mo X, Yu Y, Xiao Z, Wu J, et al

Approaches like co-carrier nanoparticles, manganese oxide-based co-delivery, copper-based ROS amplification, and biodegradable nanoparticles have all yielded promising results in preclinical models of lung, colon, and breast cancers

Notably, NAC elevated striatal levels of glycogen synthase kinase 3 (GSK3), a key regulator of dendritic structure, which led to significant recovery of dendritic complexity and spine density