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doi: 10.1016/j.ijrobp.2012.12.025 79 ShaverdianNLisbergAEBornazyanKVeruttipongDGoldmanJWFormentiSCet al

It appears the initial reduction in intensity is due to displacement of YOYO-1 via direct competitive DNA binding by the complex, while recovery at 5 and 10 M occurs due to non-competitive binding events that cause the DNA to contract, increasing the YOYO-1 density per pixel