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Description

Many natural proteins have a degron tag (left), and you can modify their cellular abundance by deleting that tag (middle) or adding an extra degron tag (right)

To this end, we treated Ly49Q transfectants (7) with methyl--cyclodextrin (mCD) (22) to deplete cholesterol in order to disrupt lipid raft organization

The role of reactive oxygen species (ROS) that are generated during the inflammatory response mediated by lymphocytes and the resulting oxidative stress has been revealed in more detail [5, 6]