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Other than this, UCB activates both extrinsic and intrinsic pathways of apoptosis as reflected by markers such as CD95, caspase-8, Bax, MMP, cytoplasmic Ca 2+ , caspase-3, and DNA fragmentation (143)

DNA fragments generated by a methylation-sensitive isoschizomer will differ in size from fragments generated by a methylation-insensitive isoschizomer