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Addressing metabolic factors, such as obesity and insulin resistance, is gaining attention, and precision medication tailors interventions to individual variations in fibrotic responses ( Understanding the mechanisms of liver fibrosis is critical for developing effective therapies

Stroke 2016, 47: 1278-1285

MAFLD can progress to metabolic dysfunction-associated steatohepatitis (MASH), a condition characterized by hepatocyte ballooning, death, and liver inflammation

In the normal myometrium, homeostasis is achieved with the assistance of matrix metalloproteinases (MMP), which are involved in remodeling and degrading certain constituents of the extracellular matrices, such as collagen, which contributes to the stiffness of ECM (Korompelis et al., 2015)