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The E3 ubiquitin ligase Trim63 (also known as MuRF1) can regulate the activity of key enzymes involved in fatty acid oxidation (FAO), such as CPT1A and ACOX1, by affecting the activity of peroxisome proliferator-activated receptor (PPAR)

Infections may also contribute to HT via molecular mimicry, in which structural or amino acid sequence similarities between microbial and human antigens induce cross-reactive immune responses, accelerating the development of autoimmunity (da Silva et al

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