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Continuing our approach from the CY 2022, CY 2023, and CY 2024 PFS final rules (86 FR 65589 and 65590, 87 FR 70155 and 701566, and 88 FR 79443 and 79444, respectively), we assume that the number of MVP registrations will equal our estimated MVP quality submissions

The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium