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Systemic inflammation, which is common in cardiovascular disease, is made possible by intestinal barrier disruption brought on by a high intake of saturated fatty acids, which enables LPS migration into the bloodstream

but, from a nutritional perspective, a more informative classification can be made between endogenous and exogenous classes

Despite the mutant embryos surviving and proliferating to embryonic day 8.5 (E8.5), the embryos become phenotypically abnormal much earlier (Bondareva et al., 2007)