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The current practice of DPN care is also considered inadequate in terms of patient journey which includes multiple visits to different clinicians having no specialist training to assess the level of risk, to provide advice, or to appropriately refer the patients for further investigation and appropriate interventions (62, 63)

Purpose: The mixture is meant to restore electrolytes, enhance hydration, and support energy production

Tewthanom, K., et al.,The effect of high dose of N-acetylcysteine in lupus nephritis: a case report and literature review.Journal of Clinical Pharmacy and Therapeutics, 2009

N-acetylcysteine (NAC), a glutathione precursor that augments intracellular antioxidant defenses, has shown otoprotective effects in three small randomized studies involving adults with end-stage renal failure receiving aminoglycosides, with pooled analysis suggesting a significant reduction in ototoxicity at 46 weeks ( in vitro studies have demonstrated that NAC may antagonize the antimicrobial efficacy of gentamicin and tobramycin, a concern that requires resolution before routine clinical adoption ( in vitro or in vivo ( Pharmacological modulation of intracellular trafficking has emerged as a preclinical research direction