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Importantly, although others C 21 steroidal glycosides (e.g., dioscin) can have potent anticancer activity by triggering mitochondrial apoptosis, caudatin is structurally unique given its incorporation of an isovalerate side chain and the C-3 glycosylation affords a broader target specificity against Wnt/-catenin and autophagy-lysosomal pathways

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Although hallmark features of asthma, COPD, and CF differ, mucus obstruction is a common attribute among all [2]