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As discussed above, PPP is the most important source of ROS production in neutrophils, producing ample NADPH for NADPH oxidase activity

Progress should be assessed through body composition analysis, circumference measurements, and photos rather than scale weight alone, as muscle preservation can mask fat loss on the scale

Four research areas dominate: tendon and ligament repair, gastrointestinal mucosal healing (ulcer and IBD models), muscle and soft tissue recovery, and neuroprotection across stroke, TBI, and demyelination models