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Inhibition of the STAT3/5 pathways in human breast cancer cells in vitro was accomplished through siRNA-mediated knock-down of the gene SLC7A11, also known ASCT (alanine, serine, cysteine transporter, xCT and solute carrier family 7)

Peer review Peer review information Nature thanks Evan Lien, Kyle McCommis and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Using genetic proxies for l-carnitine minimizes confounding, which is challenging in observational studies