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Figure 3 Potential Therapeutic Measures of TMAO for AS Reduced Production of TMAO to Protect the Heart TMAO is an intestinal microbiota-dependent metabolite, which is accumulated in the body by ingestion of large amounts of substances rich in phosphatidylcholine

The experimental design included 35 juvenile male Western albino rats, distributed into five groups of seven animals each: untreated controls, PPA alone, and PPA followed by treatment with omega-3, vitamin B12, or their combination

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