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Bulun SE, Monsavais D, Pavone ME, Dyson M, Xue Q, Attar E, et al

One example is the case of the novel acylaminoimidazole derivative, 2-[mesityl(methyl)amino]-N-[4-(pyridin-2-yl)-1H-imidazol-2-yl] acetamide trihydrochloride (WN1316) that proved to upregulate Nrf2 and regulate GSH, protecting motor neurons against OS [170] (Figure 3)