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Neuroimage 18, 19

Glutathione provides antioxidant support

On the other hand, these modifications may introduce charge heterogeneityas is commonly observed with glycosylation due to loss of sialic acid which may then complicate purification, especially with methods such as ion-exchange chromatography (UNIT 8.2)

Quantification of reduced GSH using DTNB revealed that intracellular GSH levels markedly decreased following RPTS exposure, with a reduction of 61.0% in Saos-2 cells (Control: 19.67 2.52 to RPTS: 7.67 1.53) and 66.1% in MG-63 cells (Control: 20.67 2.08 to RPTS-H: 7.00 1.00) ( Figure 2C )