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Only free, unbound fractions can diffuse across the BBB, which drastically reduces the concentration of drug available for CNS penetration

Torreilles F, Salman-Tabcheh S, Gurin M-C, Torreilles J

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Baker C, Zhu V, Rosenbaum R

Changes in beta diversity reveal that while overall species richness and evenness among the individuals were stable, LCIG can redistribute the abundance of different taxa, thereby altering cohabitation structure and interrelations among microbial species