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This could represent a novel pathogenic mechanism of particular relevance, especially for acromegaly, and underlines an exosome-mediated communication between GH-secreting pituitary adenomas and both osteoblast proliferation and bone formation

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This process suppresses the expression of antioxidants such as superoxide dismutase (SOD), resulting in oxidative stress and exacerbating inflammation [32]

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"Homocysteinea retrospective and prospective appraisal"

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