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Controlling expression of oncogenes or anti-oncogenes, on the other side, could be a lucrative tactic in the treatment of numerous types of cancer

3.5 Parallel defense pathways: GPX4, DHODH, and FSP1 Although the GPX4GSH axis is widely recognized as the primary defense line against plasma membrane lipid peroxidation and ferroptosis, recent discoveries have identified GPX4-independent parallel defense mechanisms within cells, revealing the complexity and redundancy of the cellular antioxidant network