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The feed-grade segment recorded over 68% of the L-carnitine market share in 2022, on account of its ability to strengthen the immune system, boost growth promotion and improve the antioxidant effects as well as semen quality, feed-grade L-carnitine is extensively used for poultry production

Intriguingly, PIK3C3/VPS34 lactylation augments its interaction with Beclin1, Atg14L, and UVRAG, increasing its lipid kinase activity and promoting macroautophagy/autophagy and endolysosomal degradation

In human HCC cell lines, knockdown of HMGCS2 increases tumor growth and cell migration, while HMGCS2 overexpression decreases cell proliferation and increases apoptosis (Wang et al., 2019b

Cholesterol modification of Smoothened is required for Hedgehog signaling